DETAILS, FICTION AND KETAMINE LEGAL

Metabolism Ketamine is metabolized by way of N-dealkylation to the Energetic metabolite norketamine mostly by CYP2B6 and CYP3A4 also to a lesser extent by other CYP enzymes. Norketamine undergoes hydroxylation on the cyclohexone ring to form hydroxynorketamine compounds by means of CYP-dependent pathways, which are conjugated with glucuronic acid a